Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for reducing the risk of mortality in a patient having a chronic or acute disease or acute condition

摘要

Discloses the use of an anti-adrenomedullin (ADM) antibody or an anti-adrenomedullin antibody fragment or an anti-ADM non Ig scaffold binding to adrenomedullins, in the manufacture of a medicament for therapy or prevention of SIRS, meningitis, sepsis or shock in a patient for the reduction of the mortality risk for said patient wherein said antibody fragment or non Ig scaffold binds to the N-terminal part, aa 1-21, of adrenomedullin: YRQSMNNFQGLRSFGCRFGTC (SEQ ID NO: 23).