Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy of an acute disease or acute condition of a patient for stabilizing the circulation

摘要

Discloses use of an anti-Adrenomedullin (ADM) antibody or an anti-ADM antibody fragment binding to adrenomedullin or anti-ADM non-Ig scaffold binding to adrenomedullin in the manufacture of a medicament for use in therapy of an acute disease or acute condition of a patient for stabilizing the systemic circulation of said patient, and wherein said antibody or antibody fragment or non-Ig scaffold binds to a region of at least 4 amino acids within sequence of aa1-42 of mature human ADM (SEQ ID NO: 24), wherein the sequence is as defined in the complete specification.