2-replacement bike and used as a modulator for the Oregon receiver

摘要

The invention is directed to a compound of formula, wherein X is n or CR1, y is n or CR2; R1 is h, alcoxi, halo, triazolilo, pirimidinilo, oxazolilo, isoxazol, oxadiazolilo or pirazolilo; R2 is h, tar, alcoxi or halo; Z is NH, Aquilo, alcoxi, halo or triazolilo; R4 is h or Lo; or R3 is R4 and R4, together with R4. They are combined to form an arilo ring composed of 6 members or a heteromorphic ring composed of 5 or 6 members; R5 is pyridine, pyridine or pyridine, wherein pyridine, pyridine or pyridine can be replaced by halogen or aspha n is 1 or 2. In addition, it describes a method of preparing a formula compound. The invention is interrelated, and,There are pharmacological ingredients including formula I compounds, and the use method of the compounds of the invention is also within the scope of the invention.