11 - hydroxyl Derivatives of Bile acids and amino acids (the same as farnesoid x receptor modulators

摘要

Refers to compounds 11 - hydroxyl Derivatives of Bile acids of formula (i) or a pharmaceutically acceptable acid Conjugate of hydroxyl is where R1, R2, R3, R4,R5 and R6 are as defined in the description. It also relates to a Pharmaceutical composition.These compounds are Selective agonists of the fernesoide x receptor (FXR) being useful in the treatment of cardiovascular diseases, chronic liver, Metabolic