Can add gpA33 and CD3 unit price double price slide, and use

摘要

The invention refers to two univalent binary celestial bodies, including two polypeptide chains, and at least one joint website, one is the vertex of CD3, the other is the vertex of gpA33 (i.e. "univalent Gemini" gpA33 x CD3). The invention refers to two different monovalent objects, including immunoglobulin domain ("bivalent monovalent cell group"),They are composed of three polypeptide chains, at least one specific joint website, one vertex of gpA33 and one specific joint website, one vertex of CD3 (i.e, GpA33 and CD3 can be added to a combination of dual price and dual price of "dual price FC dual price gpA33 × CD3". Invention is farm compositionThis is a slide with two unit prices or a slide with two covalent prices. The invention also relates to the use of these cells in the treatment of cancer and other diseases and diseases.