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New drug resistance, its preparation procedures, drug preparation containing drugs, and drug use

机译:新药耐药性,其制备程序,含有药物的药物制备和药物用途

摘要

The invention relates to a formula indarkaoxamidas derivative, wherein R0 is C1-C4 hydrogen or tar; R1 is hydrogen, halide, etc.; R2 is hydrogen, C1-C6 tar or C1-C6 cyclopropylsulfonyl; W is pyridine, pyridan, etc.; R13 is C1-C6 hydrogen or tar; n is 0 or 1. The most popular compounds are n - {2 - [2 - (4 - [2 - [2 - (4-benzoilpiperazin-1-il) - 2-oxyetil] - 6-meth-2h-indazol-5-il} - 6 - (trifluoromethyl) pyridine-2-carboxamida; 6-ethyl-n - (6-methyl-2 - {2-oxo-2 [4 - (pirrolidin-1-il) piperidin-1-il) ethyl} - 2h-indal-pireidin-5; and other substances. These compounds are inhibitors in Iraq.Play a role in the treatment and / or prevention of diffuse and flammable diseases such as flammable skin diseases, lung diseases, autoimmune diseases
机译:本发明涉及式Indarkaoxamidas衍生物,其中R 0为C1-C4氢或焦油; R1是氢,卤化物等; R2是氢,C1-C6焦油或C1-C6环丙基磺酰基; W是吡啶,吡啶基等; R 13为C 1 -C 6氢或焦油; n为0或1。最受欢迎的化合物是n-{2-[2-(4-[2-[2-(4-苯甲哌嗪-1-il)-2-氧etil]-6-甲基-2h-吲唑] -5-il}-6-(三氟甲基)吡啶-2-羧酰胺; 6-乙基-n-(6-甲基-2-{2-氧代-2 [4-(吡咯烷-1-il)哌啶-1-基il)乙基}-2h-吲哚-pireidin-5;以及其他物质,这些化合物在伊拉克是抑制剂。在治疗和/或预防弥散性和可燃性疾病(例如可燃性皮肤病,肺部疾病,自身免疫性疾病)中发挥作用

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