Compound exhibiting herpetic stromal antiinflammatory activity and antiviral activity, pharmaceutical compositions comprising the same, process for the preparation thereof and use thereof in the treatment of epidemic keratoconjunctivitis and keratitis

摘要

The compound of structural formula: ** ** Formula wherein R1 and R3 are selected from H, HO-, R5 -O-, HCOO-, R5-COO-, -OOC-R6-COO-, p- toluene sulfonate, phosphate, tartrate, maleate, sulfate, fluorine, chlorine, bromine, iodine and methanesulfonate, R2 is selected from H, HO-, R5 -O-, HCOO-, R5-COO-, -OOC-R6-COO -, p-toluene sulfonate, phosphate, tartrate, maleate, sulfate, fluorine, chlorine, bromine, iodine, or -R1 -R2 and may be together -O-, R4 and R5 are selected from H and C1-C4 chain straight or branched, R6 is - (CH2) n- wherein n is 1, 2 or 3, and may be a single or double bond for use in the treatment of inflammatory diseases and adenovirus.