5- (Biphenyl-4-yl) -3-phenyl-1,2,4-oxadiazolyl derivatives as ligands in sphingosine 1-phosphate (S1P) receptors

摘要

Compound of formula (I) ** Formula ** where group O ** Formula ** indicates one of the following groups: ** Formula ** Ra Hal, CH3, CHF2, CF3, CH2CH3, Rb indicates Hal, a linear alkyl or branched with from 1 to 3 carbon atoms, where from 1 to 3 H atoms can be substituted by Hal, -OCH3, -OCH2CH3, G1, G2 independently of each other indicate H, Hal, A, A indicates a linear alkyl or branched having 1 to 3 carbon atoms, where from 1 to 3 H atoms may be substituted by Hal, OCH3, OH, and pharmaceutically acceptable solvates, tautomers, salts, enantiomers and diastereoisomers thereof, including mixtures thereof in all the proportions.