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A PROCESS FOR THE PREPARATION OF CRIZOTINIB OR AN ACID ADDITION SALT THEREOF

机译:制备克唑替尼或其酸附加盐的方法

摘要

The present invention is relates to a process for the preparation of crizotinib or an acid addition salts thereof. More specifically the invention pertains to crizotinib free base in amorphous form and crizotinib dihydrochloride in crystalline and amorphous Forms and pharmaceutical compositions containing the same.
机译:本发明涉及克唑替尼或其酸加成盐的制备方法。更具体地,本发明涉及无定形形式的克唑替尼游离碱和结晶和无定形形式的盐酸克唑替尼二盐,以及含有该盐的药物组合物。

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