首页> 外国专利> FILTER HAVING OPTIMIZED EXTERNAL SHAPE OF RIDGES INSIDE FILTER

FILTER HAVING OPTIMIZED EXTERNAL SHAPE OF RIDGES INSIDE FILTER

机译:过滤器内过滤器的外部形状经过优化

摘要

A filter having a container filled with a cell separation material. The filter comprises a fluid introduction port in either an upper section or lower section of the container and a fluid discharge port on the opposite side thereto. The filter has ridges on the surface of the filled cell separation material, that protrude towards either the fluid introduction port side or the fluid discharge port side. The height (y) and the length (x) of the ridges fulfil formula (1) y = -ax2 + bx and/or formula (2) y = ax2 - bx. The ratio (a/b) between a and b is adjusted to within the range 0.03-0.25. The purpose of the present invention is to provide a cell separation filter having improved cell recovery efficiency and a cell separation method that uses the cell separation filter and whereby target cells can be efficiently recovered.
机译:一种过滤器,其具有填充有细胞分离材料的容器。该过滤器包括在容器的上部或下部中的流体引入端口以及在其相对侧上的流体排放端口。过滤器在填充的细胞分离材料的表面上具有向流体引入口侧或流体排出口侧突出的脊。脊的高度(y)和长度(x)满足公式(1)y = -ax 2 + bx和/或公式(2)y = ax 2 -bx。将a与b之间的比率(a / b)调整为0.03-0.25。本发明的目的是提供一种具有提高的细胞回收效率的细胞分离过滤器以及使用该细胞分离过滤器从而可以有效地回收靶细胞的细胞分离方法。

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