首页> 外国专利> CRYOSYRINGE DESIGNED FOR STERILE LIQUID NITROGEN FREEZING, QUICK THAWING AND INJECTION OF CELLULAR SLURRIES

CRYOSYRINGE DESIGNED FOR STERILE LIQUID NITROGEN FREEZING, QUICK THAWING AND INJECTION OF CELLULAR SLURRIES

机译:为无菌液态氮冷冻,快速融化和注射细胞浆而设计的低温注射器

摘要

An embodiment in accordance with the present invention is directed to a device for use as a cryosyringe and a cryo-storage vial. The device includes a first end and a second end and has an outer wall defining a lumen between the first and second ends. Both the first end and the second end include threads configured for attaching a first cap to the first end and a second cap to the second end. The device can also include a syringe plunger adapter, such that the cryo-storage vial is convertible into a cryosyringe to ensure sterility of the contents. Similarly, a luer-lock adapter can be included to further convert the device into a cryosyringe. The device and its components are formed from a cryo-resistant material. The device can therefore withstand liquid nitrogen temperatures necessary to preserve cell viability and be injected without compromising sterility to dispense the cellular therapy.
机译:根据本发明的实施例涉及一种用作冷冻注射器和冷冻存储瓶的装置。该装置包括第一端和第二端,并具有在第一端和第二端之间限定内腔的外壁。第一端和第二端均包括螺纹,该螺纹构造成用于将第一帽附接到第一端并且将第二帽附接到第二端。该装置还可以包括注射器柱塞适配器,使得冷冻储存瓶可以转换成冷冻注射器以确保内容物的无菌性。类似地,可以包括鲁尔锁适配器,以将装置进一步转换成冷冻注射器。该装置及其部件由抗冻材料制成。因此,该装置可以承受保持细胞活力所必需的液氮温度,并且可以在不损害分配细胞疗法的无菌性的前提下进行注射。

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