RECOMBINANT DER P 2 EXPRESSED IN PICHIA PASTORIS AS A 'NATURAL-LIKE' ALLERGEN FOR IMMUNOTHERAPY AND DIAGNOSTIC PURPOSES

摘要

#$%^&*AU2016247077A120161103.pdf#####ABSTRACT The present invention concerns a method for producing a recombinant Dermatophagoides pteronyssinus 2 protein (rDer p 2), comprising the steps of cultivating a Pichia pastoris yeast strain previously transformed with a rDer p 2 coding sequence, and isolating the rDer p 2 protein from said Pichia pastoris yeast strain. The invention also relates to compositions and kits comprising the rDer p 2 protein for therapeutic or diagnostic use.