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NANOTUBE TRANS-MEMBRANE CHANNELS MIMICKING BIOLOGICAL PORINS

机译:纳米管跨膜通道模拟生物孔蛋白

摘要

Provided herein is a nanopore structure, which in one aspect is a "carbon nanotube porin", that comprises a short nanotube with an associated lipid coating. Also disclosed are compositions and methods enabling the preparation of such nanotube/lipid complexes. Further disclosed is a method for therapeutics delivery that involves a drug delivery agent comprising a liposome with a NT loaded with a therapeutic agent, introducing the therapeutic agent into a cell or a tissue or an organism; and subsequent release of the therapeutic agents into a cell.
机译:本文提供了一种纳米孔结构,其一方面是“碳纳米管孔蛋白”,其包括具有相关脂质涂层的短纳米管。还公开了能够制备这种纳米管/脂质复合物的组合物和方法。还公开了一种用于治疗输送的方法,该方法包括药物输送剂,其包括脂质体,所述脂质体具有负载有治疗剂的NT,并将所述治疗剂引入细胞或组织或生物体中。然后将治疗剂释放到细胞中。

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