A SYSTEM AND METHOD FOR PERFORMING OPTICAL INTERFEROMETRY REFERENCING FOR OPTICAL SENSOR

摘要

The present invention relates to the sensing instruments and methods for measuring the phase measurement of an analyte more particularly, to a system and method for performing optical interferometry referencing for phase fluometric optical sensor. One of the advantages of the present invention is that the system and method provides optically the phase of the reference excitation signal at the same phase wavefront with the fluorescence excitation signal in the absent of the analyte. The method of the present invention utilizes interferometry technique to achieve a precision phase measurement. In addition, the system of the present invention engages safely the phase of excitation reference signal as the sensing system phase reference. The present invention further provides a considerable reduction of materials with even greater efficiency and economically during operation.