首页> 外国专利> METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELL LINE FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS, AND OBTAINED CELL LINE

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELL LINE FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS, AND OBTAINED CELL LINE

机译:从脂肪来源的间充质干细胞制备诱导的多能干细胞系的方法及获得的细胞系

摘要

The present invention relates to a method for preparing a pluripotent stem cell line induced from mesenchymal stem cells and the induced pluripotent stem cell line (accession number: KCLRF-BP-00319) obtained by means of same. More particularly, a method for preparing an induced pluripotent stem cell line, according to the present invention, comprises the steps of: (a) obtaining mesenchymal stem cells from human adipose tissues; (b) forming the mesenchymal stem cells into a colony by means of a dedifferentiation culture medium comprising an Ecklonia cava extract; and (c) obtaining an induced pluripotent stem cell line by subculturing the colony. An induced pluripotent stem cell line, according to the present invention, has been prepared by the inventors of the present invention for the first time. A pluripotent stem cell line, according to the present invention, can be differentiated into various cells and enables treatments of various diseases and illnesses by means of a cell transplantation therapy.
机译:本发明涉及一种由间充质干细胞诱导的多能干细胞系的制备方法以及通过该方法获得的诱导多能干细胞系(登录号:KCLRF-BP-00319)。更具体地,根据本发明的制备诱导的多能干细胞系的方法包括以下步骤:(a)从人脂肪组织获得间充质干细胞; (b)通过包含Ecklonia cava提取物的去分化培养基将间充质干细胞形成集落; (c)通过继代培养集落获得诱导的多能干细胞系。根据本发明,本发明的发明人首次制备了诱导多能干细胞系。根据本发明,多能干细胞系可以分化成各种细胞,并能够通过细胞移植疗法来治疗各种疾病。

著录项

  • 公开/公告号WO2016088928A1

    专利类型

  • 公开/公告日2016-06-09

    原文格式PDF

  • 申请/专利权人 BBHC;

    申请/专利号WO2014KR12222

  • 申请日2014-12-11

  • 分类号C12N5/0775;C12N5/074;C12N5/02;A61K35/12;

  • 国家 WO

  • 入库时间 2022-08-21 14:17:38

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