MAGNETIC TWEEZERS, CALIBRATION METHODS AND USES THEREOF

摘要

The present disclosure relates to new systems and methods for applying a force to a molecule in a controlled manner for studying molecule dynamics. An exemplary system can include a magnetic component attached to a voice coil; a substrate positioned opposite from the magnetic component for attachment to a first end of a molecule; a camera for obtaining images; and a positioning device for adjusting a focus of the camera, wherein the voice coil is configured to apply a predetermined amount of force to the molecule by adjusting a position of the magnetic component relative to a second end of the molecule.