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METHOD AND TEST KIT FOR ANALYSING POTENTIAL ACTIVE INGREDIENTS FOR TREATMENT OF KIDNEY DISEASES

机译:分析潜在的治疗肾脏疾病的有效成分的方法和测试套件

摘要

The invention relates to a method for analysing potential active ingredients for the treatment of kidney diseases, especially of podocyte-dependent kidney diseases, which comprises the following steps: a) providing isolated glomeruli which, under a promoter or promoter fragment of a podocyte-specific protein, express at least one reporter molecule, b) adding an active ingredient for analysis, and c) determining the expression of reporter molecule; and also to a corresponding test kit.
机译:本发明涉及分析用于治疗肾脏疾病,特别是足细胞依赖性肾脏疾病的潜在活性成分的方法,该方法包括以下步骤:a)提供分离的肾小球,其在足细胞特异性的启动子或启动子片段下蛋白质,表达至少一个报告分子,b)添加用于分析的活性成分,和c)确定报告分子的表达;以及相应的测试套件。

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