NO DONORS FOR THE TREATMENT OF STRESS-INDUCED PULMONARY HAEMORRHAGE IN ANIMALS

摘要

The invention relates to the field of veterinary medicine and particularly to the use of exogenous NO donors for the prevention and treatment of physical stress-induced pulmonary haemorrhage and/or associated dyspnoea in animals of the family Equinea, CamelicJae or Canidae. More particularly the invention relates to amino-C₂- C₆-alkyl nitrates or amino-C₂-C₄-alkyl nitrates and the pharmaceutically acceptable salt thereof, for the acute or chronic treatment of stress-induced pulmonary haemorrhage and/or associated dyspnoea in animals of the family Equinea, Camelidae or Canidae with the objective to accelerate the recovery and the healing process after a lung bleeding event. The invention also relates to the use of said amino-alkyl nitrates and the pharmaceutically acceptable salt thereof as an oral dosage form or in the form of an extended release composition. The most preferred amino-alkyl nitrate in accordance with the invention is 2-aminoethyl nitrate.