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SUSTAINED RELEASE GASTRORETENTIVE TABLETS

机译:持续发售的胃片

摘要

The present invention relates to sustained release gastroretentive tablets for controlling gastric retention and release of a drug and, more specifically, to sustained release gastroretentive tablets floating/retaining in stomach while controlling release thereof soon after taking the same. The present invention easily controls release of the drug by not being affected by pH in the stomach, floating soon after meeting gastric juice, and adjusting content % of a release controlling agent. Therefore, the present invention can retain in the stomach without transition to small intestine and continuously release an active ingredient for a long time in case of oral administration even under the environment the pH and amount of the gastric juice are drastically changed depending on a diet, such as hypochlorhydria patients, administration before meals, and in case of a decrease in pH in the stomach or lack of gastric juice.;COPYRIGHT KIPO 2016
机译:本发明涉及用于控制药物在胃中的滞留和释放的缓释胃滞留片剂,更具体地说,涉及在胃中漂浮/保留在胃中的缓释胃滞留片剂,在服用后立即控制其释放。本发明不受胃中pH的影响,在遇到胃液后不久就漂浮,并调节释放控制剂的含量%,从而容易地控制药物的释放。因此,本发明可以保留在胃中而不过渡到小肠,并且即使在环境下,根据饮食,胃液的pH值和量会发生剧烈变化,口服给药也可以长时间长时间释放活性成分。例如胃酸过少的患者,饭前服用以及胃中pH降低或胃液不足的情况。; COPYRIGHT KIPO 2016

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