Provided is a coolant loss analysis system and method for minimizing a human error, analyzing a time loss, and improving a quality control efficiency in analyzing a loss of a coolant loss accident It has its purpose. To achieve these and other advantages and in accordance with the purpose of the present invention, as embodied and broadly described herein, there is provided an apparatus for estimating a set of uncertainty parameters, comprising: a sampling unit configured to generate a plurality of sets by assigning arbitrary values to respective variables; An input generator for reflecting a value of each uncertainty variable generated through the sampling unit to a code input for simulating a power plant; A calculation unit for performing an actual calculation using the input generated through the input generation unit; A data extracting unit for extracting necessary data from the result files calculated through the calculating unit; And an evaluation result deriving unit for deriving a final evaluation result based on the data extracted through the data extracting unit; .
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