FABRICATION OF POLY (-CAPROLACTONE)/SILICA COMPOSITE SCAFFOLD

摘要

The present invention relates to a method for preparing a scaffold and a scaffold prepared by the same. According to the present invention, a scaffold having advantages of poly(-caprolactone) (PCL), or a biocompatible polymer and silica with bone-inducing properties is prepared to establish an environment beneficial to cell proliferation, thereby having excellent mechanical properties and initial cell attachment rate. In addition, the scaffold of the present invention has a stable three-dimensional structure, a big size of a pore, and high interconnectivity between pores to effectively supply oxygen and nutrients necessary for survival and growth of cells, thereby providing excellent efficiencies of cell survival, growth, and differentiation. Furthermore, silica can be coated in various concentrations to control growth and differentiation of cells, thereby enabling a user to prepare scaffolds suitable to conditions of various patients. Accordingly, the scaffold of the present invention can be useful in a field of regenerating bone tissues and various tissues.