The present invention relates to a method for predicting earthquake damage of an evaluation target area in real time based on a geographic information system (GIS) by managing measuring information, ground investigating information, and structure information collected from an earthquake measuring machine installed to measure a seismic wave of the evaluation target area when an earthquake occurs, and evaluating in connection with the management. The method for predicting earthquake damage in real time based on a GIS comprises the following steps: (A) an operation processing unit draws a correlation between a bedrock outcrop acceleration of the seismic wave and a maximum acceleration for each stratum through a land response analysis according to a ground condition and an earthquake acceleration condition based on a three-dimensional spatial model; the operation processing unit determines a possibility to have liquefraction with a cell unit through a ground property analysis based on the three-dimensional spatial model, and selects a liquefraction evaluation target; and (C) the operation processing unit draws a maximum acceleration of the seismic wave for each cell by receiving a measurement value of the bedrock outcrop acceleration of the seismic wave from an earthquake measuring unit, estimating a cyclic shear stress ratio (CSR) and a cyclic resistance Ratio (CRR) of cells selected as a ground likely to have liquefraction, and draws a liquefraction safety factor (FS_liquefraction) for each cell and a liquefraction damage level.
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