首页> 外国专利> COMPOSITION FOR ENHANCING IMMUNE ACTIVITY COMPRISING MILK PROTEIN WITH HIGH CONTENT OF ORGANIC SELENIUM AS AN ACTIVE INGREDIENT AND PREPARATION METHOD THEREOF

COMPOSITION FOR ENHANCING IMMUNE ACTIVITY COMPRISING MILK PROTEIN WITH HIGH CONTENT OF ORGANIC SELENIUM AS AN ACTIVE INGREDIENT AND PREPARATION METHOD THEREOF

机译:包含高含量有机硒的乳蛋白增强活性成分的免疫活性成分及其制备方法

摘要

Provided are a composition for enhancing immunity, containing a milk protein with a high content of organic selenium as an active ingredient, and a method for preparing the same. The milk protein with a high content of organic selenium prepared by mixing mixed powder, which is prepared by mixing whey powder and selenium power, with water and then heating the same, increases the bioavailability of minerals. In addition, the composition has immune enhancing activities by: increasing the number of immune cells such as macrophages, neutrophils, monocytes, etc., which primarily defend against pathogenic microorganisms, and natural killer (NK) cells in the blood; increasing the number of CD4 positive helper T cells (T_H cells) and CD8 positive cytotoxic T cells (T_C cells) in lymph nodes; and increasing the secretion of tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), the immune-related cytokines secreted from activated macrophages, when the composition is orally administrated, thereby being able to be used as an active ingredient of a food composition or a pharmaceutical composition for enhancing immunity.
机译:本发明提供含有高有机硒含量的乳蛋白作为有效成分的增强免疫力的组合物及其制备方法。通过将乳清粉和硒粉混合并与水混合然后加热,可以将混合粉末混合在一起,从而制备出具有高有机硒含量的牛奶蛋白,从而提高了矿物质的生物利用度。另外,该组合物通过以下方式具有免疫增强活性:增加主要防御病原微生物的免疫细胞,例如巨噬细胞,嗜中性粒细胞,单核细胞等,以及血液中的自然杀伤(NK)细胞。增加淋巴结中CD4阳性辅助T细胞(T_H细胞)和CD8阳性细胞毒性T细胞(T_C细胞)的数量;当口服给予该组合物时,可增加活化的巨噬细胞分泌的免疫相关细胞因子肿瘤坏死因子-(TNF-)和白细胞介素-1(IL-1)的分泌,从而可以用作活性成分用于增强免疫力的食品组合物或药物组合物的成分。

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