首页> 外国专利> AMORPHOUS ALLISARTAN ISOPROXIL, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING AMORPHOUS ALLISARTAN ISOPROXIL

AMORPHOUS ALLISARTAN ISOPROXIL, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING AMORPHOUS ALLISARTAN ISOPROXIL

机译:异典异戊二烯异方胺,其制备方法和包含异典异丁香异方体的药物组合物

摘要

The present invention relates to an amorphous form of Allisartan isoproxil, which is an angiotensin II receptor antagonist. The amorphous form has high fluidity, high bulk density and no significant electrostatic phenomenon. By discovering the amorphous form, it is possible not only to reduce the generation of dust in the production process, but also to provide convenience in the production process of Allisartan isoproxil. The present invention also relates to a pharmaceutical composition containing an amorphous form of Allisartan isoproxil, and the above-mentioned pharmaceutical composition has high stability. Therefore, the Allisartan isoproxil tablets prepared from the above pharmaceutical composition can effectively ensure the quality of medicines.
机译:本发明涉及Allisartan isoproxil的无定形形式,其是血管紧张素II受体拮抗剂。无定形形式具有高流动性,高堆积密度并且没有明显的静电现象。通过发现无定形形式,不仅可以减少生产过程中粉尘的产生,而且还可以为阿里沙坦异吡咯酯的生产过程提供便利。本发明还涉及含有无定形形式的Allisartan isoproxil的药物组合物,并且上述药物组合物具有高稳定性。因此,由上述药物组合物制备的阿利沙坦异吡咯烷酮片可以有效地保证药物质量。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号