24- -15- 24-Disubstituted phenylene-15-Diamine Derivatives and Applications Thereof and Pharmaceutical Compositions and Pharmaceutically Acceptable Compositions Prepared Therefrom

摘要

The present invention provides 2,4-disubstituted phenyl-1,5-diamine derivatives and pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs thereof having an inhibitory action on EGFR tyrosine kinase. Detailed definitions of each radical in the formula can be found in the specification. In addition, the present invention further discloses drug compositions, medicinal compositions and their applications of the above compounds.