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.Delayed-release microspheres containing risperidone and a method for manufacturing the same

机译:含有利培酮的缓释微球及其制备方法

摘要

The present invention relates to a formulation for controlling a speed of drug release of a delayed-release microsphere containing risperidone, and relates to a manufacturing method thereof. According to the present invention, the formulation for controlling a speed of drug release of the delayed-release microsphere containing a biodegradable polymer controls the time and the volatilization temperature above the glass transition temperature (Tg), thereby controlling the speed of drug release and reducing the manufacturing time and the residual solvent. The formulation for controlling a speed of drug release of the delayed-release microsphere containing a biodegradable polymer can be significantly used as an effective means for delivering bioactive drugs inside the body in a medical industry field.
机译:本发明涉及用于控制含有利培酮的缓释微球的药物释放速度的制剂,并且涉及其制备方法。根据本发明,用于控制含有可生物降解的聚合物的缓释微球的药物释放速度的制剂将时间和挥发温度控制在玻璃化转变温度(Tg)以上,从而控制药物释放的速度并降低药物的释放。制造时间和残留溶剂。控制含有生物可降解聚合物的缓释微球的药物释放速度的制剂可以显着用作在医疗工业领域中将生物活性药物传递到体内的有效手段。

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