2 2 A two-photon probes for Copper-ion and quantitative estimation of Copper-ion in human tissues using the same

摘要

the invention copper 2 by using in vivo imaging for Localization two-photon marker, and it has a selectivity for ions to a method for in vivo copper 2 quantified the concentration of the ion, two-photon probes according to the invention Markers can be living cells and have a high penetration depth of 90 [micro] m than within the tissue without targeting and light discoloration problems of O 2 is the glass cell for a long period of time detecting a copper ion, a blue light-emitting intensity in the region 400-450 nm and 550 using the light intensity ratio of the intensity of the red light emitting region -650 nm divalent copper in vivo to quantify the concentration of the ion. ;