4 - Novel tetranuclear arene-Ru based metalla-bowls compound and pharmaceutical composition for preventing or treating cancer containing the same as active ingredient

摘要

The present invention relates to a novel 4-nuclear arene-ruthenium-based bowel compound or a pharmaceutically acceptable salt thereof, which is useful for the treatment of human HCT-15 (rectal cancer), SK-hep-1 (liver cancer) and AGS Inhibits proliferation at a low micromolar concentration, exhibits excellent anticancer activity by inhibiting the activity of cancer cells by increasing the expression of a tumor suppressor, and thus can be effectively used for prevention and treatment of cancer.