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A composition for having both anti-aging and anti-inflammation activities by UV comprising rhamnetin

机译:包含鼠李素的通过紫外线具有抗衰老和抗炎活性的组合物

摘要

The present invention relates to the use of the low cytotoxicity of 2- (3,4-dihydroxyphenyl) -3,5-dihydroxy-7-mesosilcomene-4-one, The present invention also relates to a use of a substance exhibiting excellent anti-inflammatory activity by suppressing the production of nitrite oxide and cytokine, which are inflammatory inducers, and a signaling mechanism. In addition, it confirmed that it suppressed the formation of MMPs, which is the degradation factor of collagen after irradiation with ultraviolet rays, and has the effect of improving the aging and wrinkles. It suppresses the phosphorylation of ac, p38 map kinase and quasi-kinase, And suggests the possibility of its use as a cosmetic product.
机译:本发明涉及2-(3,4-二羟基苯基)-3,5-二羟基-7-间甲硅油-4-酮的低细胞毒性的用途,本发明还涉及显示出优异的抗细胞毒性的物质的用途。 -通过抑制亚硝酸盐和细胞因子(它们是炎症诱导剂)的产生来抑制炎症活动,以及信号传导机制。另外,证实了其抑制了MMP的形成,该MMP是紫外线照射后胶原的降解因子,并且具有改善衰老和皱纹的作用。它可以抑制ac,p38图激酶和准激酶的磷酸化,并暗示其可用作化妆品的可能性。

著录项

  • 公开/公告号KR101604257B1

    专利类型

  • 公开/公告日2016-03-17

    原文格式PDF

  • 申请/专利权人 건국대학교 산학협력단;

    申请/专利号KR20140065427

  • 发明设计人 김양미;이은정;

    申请日2014-05-29

  • 分类号A61K31/352;A61K8/49;A61P17;A61Q17/04;

  • 国家 KR

  • 入库时间 2022-08-21 14:12:50

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