Composition for radiation protection comprising diplacone flavonoid compounds isolated from Paulownia coreana

摘要

The present invention relates to a radioprotective composition containing, as an active ingredient, a diplacone-based flavonoid compound separated from a paulownia tree, and more particularly, to a composition for protecting radiation from diplacone, 3'-O-methyl-5'- O-methyl-5'-hydroxydiplacone, 3'-O-methyl-5'-O-methyldipracone and 3'-O (3'-O-Methyldiplacol) as an active ingredient has the effect of eliminating oxygen radicals, which are harmful active oxygen generated upon irradiation with radiation, It has an effect of inhibiting DNA damage, has an effect of suppressing cell death, and has no toxicity and few side effects, so that it can be useful in various work environments where there is a possibility of being exposed to radiation because it is safe for human body.