ID-56D2 A composition comprising the compoundsID-56D2 isolated from an extract of Ixeris dentata NAKAI for treating or preventing xerostomia

摘要

invention sseumbagwi extract from the separation of the compounds contained as an effective ingredient for the prevention and treatment of xerostomia for the composition according to the invention in accordance sseumbagwi extract (1) the salivary gland cells (human salivary gland cells, in experiments using HSG cells), sseumbagwi with a high concentration of glucose promotes the simultaneous treatment of amylase secretion, as well as decreasing the expression of endoplasmic reticulum stress-related protein, (6) short-term and long-term high concentration at the time of glucose and simultaneous processing the oxidation associated with the endoplasmic reticulum protein synthesis - by check the reducing environment is maintained well, it can be usefully used as a preventive and therapeutic pharmaceutical composition and health food for the dry mouth ;