SYNTHESIS OF FURAN THIOPHENE AND PYRROLES FROM ACETOACETIC ESTERS

摘要

The present invention relates to a process for the synthesis of furan, thiophene and pyrrole using acetoacetic ester, and more particularly to a process for the synthesis of furan, thiophene and pyrrole by using acetoacetic ester, (III) / cobalt (II) catalyst was applied to a 1,4-dicarbonyl compound to synthesize a 1,4-dicarbonyl compound. Then, the synthesis of furane, thiophene, pyrrole And a method for synthesizing the compound. According to the present invention, the 1,4-dicarbonyl compound necessary for the synthesis of Paal-Knorr can be efficiently and easily synthesized, and the oxidation reaction (deacetylation reaction) and the Paal- Pot synthesis method of furan, thiophene, and pyrrole in which two reactions are sequentially carried out in one reaction vessel in conjunction with the Knorr synthesis method.