1515- 2 HAIR GROWTH PROMOTING AGENT CONTAINING 1515-DIFLUOROPROSTAGLANDIN F2 DERIVATIVE AS ACTIVE INGREDIENT

摘要

The present invention provides a new pharmaceutical use of the 15,15-difluoro prostaglandin F _2? Derivatives. As a result of intensive studies to find a new medicinal use of the 15,15-difluorostaglandan F _2? Derivatives, it has been found that the use of the 15,15-difluoro-prostaglandin F _2α derivative, tafloprost, In a Phase III clinical trial in Europe, it was found that such a fluffrost has the effect of promoting the growth of the eyelash, bristle and discoloration, that is, the stimulation of hair (eyelash growth). Therefore, the 15,15-difluoroprostastiglucan F _2? Derivatives are useful as a hair growth promoter and are useful as a preventive or therapeutic agent for diseases caused by hair such as alopecia and hair care products or hairs for hair growth, hair growth, And is expected to be useful as an active ingredient of cosmetics.