POLYMER-FREE EVEROLIMUS DRUG ELUTION STENT FOR BLOOD VESSEL USING ELECTROSPINNING TECHNIQUE

摘要

A drug elution stent for a blood vessel of the present invention can precisely control the total content of bound everolimus-based drugs and has effects in forming a uniform layer, even if a polymer causing post-thrombotic syndrome or the like, by using electrospinning. The drug elution stent comprises: a stent; a nitrogen-doped titanium oxide layer formed on the stent; a surface-coupled functional group including a hydroxyl group; and ester-bound everolimus-based drugs and physically-bound everolimus-based drugs, bound to the surface-coupled functional group.;COPYRIGHT KIPO 2016