Multi-layered hybrid scaffold with porous biodegradable and controlled-release for simultaneous regeneration of soft and hard tissues

摘要

A polymer hydrogel is formed in the pores of the porous and biodegradable polymer scaffold and on one or both surfaces of the polymer scaffold. The polymer hydrogel is formed by a Michael type addition reaction mechanism which does not use a crosslinking agent separately Layer hybrid support. RTI ID = 0.0 A / RTI The multilayer hybrid support of the present invention can simultaneously regenerate the soft tissue and the hard tissue.