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COMBINATIONS OF SAPACITABINE OR CNDAC WITH DNA METHYLTRANSFERASE INHIBITORS SUCH AS DECITABINE AND PROCAINE
COMBINATIONS OF SAPACITABINE OR CNDAC WITH DNA METHYLTRANSFERASE INHIBITORS SUCH AS DECITABINE AND PROCAINE
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机译:沙巴他滨或CNDAC与DNA甲基转移酶抑制剂如地他滨和普鲁卡因的组合
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摘要
The first aspect of the present invention relates to a DNA methyltransferase inhibitor and 1- (2-C-cyano-2-deoxy- beta -D-arabino-pentofuranosyl) -N4-palmitoyl cytosine or a metabolite thereof . / RTI A second aspect of the present invention relates to a method for the production of a DNA methyltransferase inhibitor comprising the steps of reacting a DNA methyltransferase inhibitor with 1- (2-C-cyano-2-deoxy- beta -D-arabino-pentofuranosyl) As a combination preparation for simultaneous, sequential or separate use in a therapy. A third aspect of the present invention relates to the use of a DNA methyltransferase inhibitor and 1- (2-C-cyano-2-deoxy- beta -D-arabino-pentofuranosyl) -N4-palmitoyl cytosine or its metabolism Comprising administering the product to a subject simultaneously, sequentially or separately.
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