HYALURONIC ACID AND ITS APPLICATION IN TREATMENT OF VENOUS DEFICIENCY AND VARICOSE EXPANSION OF VEINS

摘要

1. Viscous aqueous solution for injection with a half-life in the connective tissue of a person more than 1 week for use in the treatment of vein diseases characterized by dilated veins. 2. A solution according to claim 1, comprising one or more of the following compounds: polylactic acid, alginate and hyaluronic acid. 3. A solution according to claim 2, comprising from 0.1% to 3% hyaluronic acid, preferably cross-linked 1,4-butanediol diglycidyl ether (BDDE). 4. A solution according to claim 2, wherein the concentration of hyaluronic acid is from 0.25% to 2%, preferably from 0.5 to 1%. The solution of PP. 2-4, in which the molecular weight of hyaluronic acid is from 1 million to 8 million Da. 6. The solution of PP. 1-4, further comprising a local anesthetic. 7. The solution of claim 6, wherein the local anesthetic is from the group consisting of scandicain, mepivacaine, cocaine, procaine, benzocaine (ethoform), lidocaine, mepivacaine, bupivacaine, ropivacaine, ethidocaine, prilocaine and tetracaine. 8. The solution of PP. 1-4, in which the disease of the veins is selected from the group comprising aneurysm, varicose veins, venous insufficiency, veins and ectasia. 9. A catheter system comprising a cannula for vascular puncture with a double or triple cut of the tip, including, (i) an external cannula (non-cutting element), a tube-like construction, characterized by some flexibility, in which (a) the zone narrows to facilitate insertion, (b) the edges, possibly rounded to ensure atraumatic movement, (c) possibly contains a connector with a Luer-lock type connector, (ii) a flexible and bendable hollow needle, (a) which possibly contains a transparent pavilion, and (b) the diameter of the needle is smaller than the diameter of the outer part , and ( iii) the needle and external cannula are connected by a temporary connector for