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The pharmaceutical composition of statins with prebiotics for treatment of hypercholesterolemia and hyperlipidemia

机译:他汀类药物与益生元的药物组合物,用于治疗高胆固醇血症和高脂血症

摘要

1. A pharmaceutical composition for treating hypercholesterolemia, triglyceridemia, coronary heart disease (CHD), and prevention of myocardial infarction, stroke, atherosclerosis comprising at least two active components, wherein one component selected from the group of statins and the second component from the group of prebiotics , with the following component in the composition, by weight, mg:. 2. A pharmaceutical composition according to claim 1, characterized in that the composition comprises as a prebiotic:. Xylitol, sorbitol, lactitol, lactulose, laktosukrozu, melibiose, xylobiose, stachyose, raffinose, or fructooligosaccharide, galactooligosaccharide, maltooligosaccharide, xylooligosaccharide, isomaltooligosaccharides, gentioligosaharid or arabinogalactan , pectin, pullulan, inulin.3. A pharmaceutical composition according to claim 1, characterized in that it comprises statins from the group:. Atorvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin, fluvastatin, pitavastatin.4. A pharmaceutical composition according to claim 1, characterized in that the composition is in a dosage form for oral administration:. Tablets, powders, cachets, pellets, granules, oral suspension, oral solution, kapsuly.5. A pharmaceutical kit for the treatment of hypercholesterolemia, triglyceridemia, ischemic heart disease, and prevention of myocardial infarction, stroke, atherosclerosis placed into acceptable packing comprising at least two active components, wherein one component selected from the group of statins and the second component from the group of prebiotics, in the following Content of components in the composition, by weight, mg:. 6. A pharmaceutical composition according to claim 5, characterized in that the composition comprises as a prebiotic:. Xylitol, sorbitol, lactitol, la
机译:1.一种用于治疗高胆固醇血症,甘油三酯血症,冠心病(CHD)并预防心肌梗塞,中风,动脉粥样硬化的药物组合物,其包含至少两种活性成分,其中选自他汀类药物的一种组分和选自他汀类药物的第二种组分益生元,在组合物中具有以下成分,按重量计: 2.根据权利要求1的药物组合物,其特征在于所述组合物包含作为益生元:。木糖醇,山梨糖醇,乳糖醇,乳果糖,laktosukrozu,蜜利比糖,木糖,水苏糖,棉子糖或低聚果糖,低聚半乳糖,麦芽低聚糖,木寡糖,异麦芽低聚糖,龙胆寡糖或阿拉伯半乳糖聚糖,果胶。 2.根据权利要求1的药物组合物,其特征在于它包含选自以下组的他汀类:阿托伐他汀,洛伐他汀,普伐他汀,瑞舒伐他汀,辛伐他汀,氟伐他汀,匹伐他汀4。 2.根据权利要求1所述的药物组合物,其特征在于,所述组合物为用于口服的剂型。片剂,散剂,扁囊剂,丸剂,颗粒剂,口服混悬剂,口服溶液,卡普苏里5。放置在可接受的包装中的用于治疗高胆固醇血症,甘油三酯血症,缺血性心脏病以及预防心肌梗塞,中风,动脉粥样硬化的药物试剂盒,其包含至少两种活性成分,其中选自他汀类药物的一种组分和选自他汀类药物的第二种组分一组益生元,以下成分在成分中的含量,以重量计,mg: 6.根据权利要求5的药物组合物,其特征在于所述组合物包含作为益生元:。木糖醇,山梨糖醇,乳糖醇,拉

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