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METHOD FOR PREDICTION OF MODERATE SEVERITY OF CHRONIC TRUE ECZEMA

机译:预测慢性真性湿疹严重程度的方法

摘要

FIELD: medicine.;SUBSTANCE: DNA is recovered from peripheral blood, and -308G/A TNFα,+250A/G Ltα,+1663A/G TNFR2 gene polymorphisms or their combinations are analysed. The high risk of the moderate severity of chronic true eczema is predicted if observing +250G Ltα allele or a combination of +250G Ltα allele and +1663G TNFR2 allele, or a combination of -308A TNFα allele and +1663G TNFR2 allele, or a combination or -308G TNFα allele and +250G Ltα allele. The low risk of the moderate severity of chronic true eczema is predicted if -308G TNFα allele is stated to combine with +250AA Ltα genotype.;EFFECT: more accurate prediction.;5 ex
机译:领域:药物;研究对象:从外周血中回收DNA,并分析-308G / ATNFα,+ 250A / GLtα,+ 1663A / G TNFR2基因多态性或其组合。如果观察+ 250GLtα等位基因或+ 250GLtα等位基因与+ 1663G TNFR2等位基因的组合,或-308ATNFα等位基因与+ 1663G TNFR2等位基因的组合,或两者结合,则预示着中度严重慢性湿疹的高风险或-308GTNFα等位基因和+ 250GLtα等位基因。如果说-308GTNFα等位基因与+ 250AALtα基因型结合,则可以预测到发生中度严重慢性湿疹的风险较低。效果:更准确的预测。5ex

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