METHOD FOR DELIVERY OF BORON-CONTAINING PREPARATIONS FOR BORON NEUTRON CAPTURE THERAPY

摘要

FIELD: medicine.;SUBSTANCE: invention relates to method for delivery of boron-containing preparations (¹⁰B) for boron neutron-capture therapy (BNCT), for delivery of boron-containing preparations into cells using pegylated liposomes. At that, when preparing liposomes, additionally luminescent dye of one colour is introduced into lipid part of liposomes, and luminescent dye of another colour - into aqueous part of liposomes, and control of delivery into cell is carried out by comparing images obtained in both colours with help of fixing device.;EFFECT: invention provides high reliability of delivery of boron-containing preparations for BNCT inside tumour cells, and can enable both determination of intracellular boron concentration in different moments of time and determination of maximum intracellular boron concentration required to achieve maximum effect from BNCT.;7 cl, 4 dwg