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GENE EXPRESSION PROFILING BASED IDENTIFICATION OF GENOMIC SIGNATURES OF HIGH-RISK MULTIPLE MYELOMA

机译:基于基因表达谱的高危多发性骨髓瘤基因特征识别

摘要

The present invention discloses a method of gene expression profiling to identify genomic signatures linked to survival specific for a disease and a kit that can be used for performing such a method. Also disclosed herein is the use of such a method in classifying the disease into subsets, predicting clinical outcome and survival of an individual, selecting treatment for an individual suffering from a disease, predicting post-relapse risk and survival of an individual, correlating molecular classification of a disease with genomic signature defining the risk group or a combination thereof.
机译:本发明公开了一种用于鉴定与疾病的特异性存活相关的基因组特征的基因表达谱分析方法,以及一种可用于执行这种方法的试剂盒。本文还公开了这种方法在将疾病分类为亚类,预测个体的临床结果和生存,为患有疾病的个体选择治疗,预测复发后风险和个体生存,关联分子分类中的用途。具有定义风险组的基因组特征的疾病或其组合。

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