首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR TREATING FLT3 MUTATION-POSITIVE CANCER, FLT3 MUTANT INHIBITOR, AND USE OF SAID PHARMACEUTICAL COMPOSITION AND SAID INHIBITOR

PHARMACEUTICAL COMPOSITION FOR TREATING FLT3 MUTATION-POSITIVE CANCER, FLT3 MUTANT INHIBITOR, AND USE OF SAID PHARMACEUTICAL COMPOSITION AND SAID INHIBITOR

机译:用于治疗FLT3突变阳性癌症,FLT3突变抑制剂的药物组合物,以及使用所述药物组合物和所述抑制剂的用途

摘要

Provided are a pharmaceutical composition for treating an FLT3 mutation-positive cancer; a mutant FLT3 inhibitor; and uses thereof. Disclosed are a pharmaceutical composition for treating an FLT3 mutation-positive cancer, containing a compound represented by General Formula [1] or a salt thereof as an active ingredient; a mutant FLT3 inhibitor; an anticancer agent; a method for predicting a therapeutic effect by administration of a pharmaceutical composition containing a compound represented by General Formula [1] or a salt thereof in a subject, including a step of detecting the presence or absence of an FLT3 mutation; a method for selecting a subject to whom a pharmaceutical composition containing a compound represented by General Formula [1] or a salt thereof is applied, including a step of detecting the presence or absence of an FLT3 mutation; and a method for determining whether or not a pharmaceutical composition containing a compound represented by General Formula [1] or a salt thereof is administered to a subject, including a step of detecting the presence or absence of an FLT3 mutation.
机译:提供了用于治疗FLT3突变阳性癌症的药物组合物;突变的FLT3抑制剂;及其用途。本发明公开了一种用于治疗FLT3突变阳性癌症的药物组合物,其包含通式[1]表示的化合物或其盐作为有效成分。突变的FLT3抑制剂;抗癌剂;通过在受试者中施用包含通式[1]表示的化合物或其盐的药物组合物来预测治疗效果的方法,包括检测FLT3突变的存在或不存在的步骤;本发明涉及选择含有通式[1]表示的化合物或其盐的药物组合物的对象的方法,包括检测FLT3突变的有无的步骤。确定包含通式[1]表示的化合物或其盐的药物组合物是否被施用于对象的方法,包括检测FLT3突变的存在或不存在的步骤。

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