KITS AND METHODS FOR DETECTING DRUG-INDUCED DEAFNESS SUSCEPTIBILITY

摘要

The present invention provides a detection kit for detecting the mitochondrial gene C1494T and A1555G mutations associated with maternally inherited aminoglycoside-induced deafness. The kit comprises 2 pairs of primers with the nucleotide sequences set forth in SEQ ID NO: l, SEQ ID NO:2, SEQ ID NO:5, and SEQ ID NO:6, and 3 TaqMan-MGB probes with the nucleotide sequences set forth in SEQ ID NO:3, SEQ ID NO:4, and SEQ ID NO:7.