MRNA AND/OR PROTEIN OF ERCC1 ISOFORM 3 FOR USE IN DIAGNOSING A RESISTANCE AGAINST A THERAPEUTIC AGENT AND METHOD FOR DIAGNOSING A RESISTANCE AGAINST A THERAPEUTIC AGENT USING SAID MRNA AND/OR PROTEIN

摘要

A method for diagnosing a resistance against a therapeutic agent in a patient, which includes measuring an amount of ERCC1 isoform 3 protein and/or an amount of ERCC1 isoform 3 mRNA, which present in a liquid sample or a tissue sample obtained from the patient, and comparing the measured amount to a predetermined value, wherein an amount above the predetermined value indicates resistance against said therapeutic agent.