Embodiments of systems, non-transitory computer-readable medium having one or more computer programs stored therein, and computer-implemented methods are provided to enhance probing of hydrocarbon reservoir simulation models. Embodiments can utilize an application programming interface (API) to interrogate one or more different hydrocarbon reservoir simulation response surface model proxies (surface model proxies) associated with hydrocarbon reservoir simulation models. The API (a proxy API) can be configured to include preselected operations, and surface model proxies can be in a common image format. Surface model proxies can be interpreted to retrieve simulation data associated with the surface model proxies responsive to operations of the proxy API. Results of operations of the proxy API can also be displayed to probe a hydrocarbon reservoir simulation model associated with a surface model proxy and to thereby estimate probabilities of simulation outcome for potential simulation scenarios yet to be run.
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