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METHOD FOR PREPARING IMPROVED INTERMEDIATE FOR PRODUCING HIGH-PURITY PEMETREXED AND METHOD FOR PRODUCING HIGH-PURITY PEMETREXED USING INTERMEDIATE
METHOD FOR PREPARING IMPROVED INTERMEDIATE FOR PRODUCING HIGH-PURITY PEMETREXED AND METHOD FOR PRODUCING HIGH-PURITY PEMETREXED USING INTERMEDIATE
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机译:制备用于生产高纯度聚乙烯醇的改进中间体的方法和使用中间体制备高纯度聚乙烯醇的方法
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摘要
The present invention relates to a method for preparing an improved intermediate for producing high-purity pemetrexed and a method for producing high-purity pemetrexed using the intermediate, and more specifically, to a novel method for preparing pemetrexed diethyl ester, which is an intermediate for producing pemetrexed, or a salt thereof with high purity, and to a method for producing pemetrexed disodium salt with high purity using the intermediate.
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