IDENTIFICATION OF JC VIRAL EPITOPES BY CYTOTOXIC T LYMPHOCYTES IN HEALTHY INDIVIDUALS AND THEIR USE IN ASSAYS

摘要

The invention relates to a method to predict the onset and/or development of PML in a patient or in an immunosuppressed patient by detection of JCV specific CTL's in blood of said patient using any of the ten (10) JCV amino acid sequences SEQ ID NO 1-10 separately or in combination with each other.