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SYSTEM, COMPUTER-IMPLEMENTED METHOD AND COMPUTER PROGRAM PRODUCT FOR INDIVIDUALIZED MULTIPLE-DISEASE QUANTITATIVE RISK ASSESSMENT

机译:个性化多病态量化风险评估的系统,计算机实现方法和计算机程序产品

摘要

System for individualized multiple-disease quantitative risk assessment, comprising:- a database (110) storing clinical data of patients with prognostic variables including biological signals (118);- an analysis module (114) for processing the biological signals (118) for a given patient to automatically calculate prognostic parameters (120) of diagnostic relevance for said patient;- a risk-evaluation module (116) for estimating, using a risk-evaluation model that considers predictor variables among the prognostic variables stored in the database (110) and the prognostic parameters (120) calculated by the analysis module (114), an individualized hazard ratio (122) of having an event or developing a medical condition within a given period of time for the given patient; and- an individualized multiple-disease quantitative risk assessment module (124) for computing, based on the risk-evaluation model and specified thresholds for each of the predictor variables, a quantification of the risk (126) for the given patient for each of the events or medical conditions under evaluation.
机译:个性化多病定量风险评估系统,包括:-数据库(110),其存储具有包括生物信号在内的预后变量的患者的临床数据(118);-分析模块(114),用于处理给定患者的生物信号(118),以自动计算对该患者的诊断相关性的预后参数(120);-风险评估模块(116),用于使用考虑数据库(110)中存储的预测变量和由分析模块(114)计算的预测参数(120)之中的预测变量的风险评估模型来评估风险评估模块(116)。针对给定患者在给定时间内发生事件或发展为医疗状况的个体风险比(122);和-个体化的多种疾病定量风险评估模块(124),用于基于风险评估模型和每个预测变量的指定阈值来计算给定患者每个事件的风险量化(126)或评估中的医疗状况。

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