首页> 外国专利> RECOMBINANT MONOCLONAL ANTIBODY AND CORRESPONDING ANTIGEN FOR COLORECTAL CANCER AND PANCREATIC CANCER

RECOMBINANT MONOCLONAL ANTIBODY AND CORRESPONDING ANTIGEN FOR COLORECTAL CANCER AND PANCREATIC CANCER

机译:大肠癌和胰腺癌的重组单克隆抗体和相应抗原

摘要

PROBLEM TO BE SOLVED: To provide a human colorectal and pancreatic carcinoma-associated antigen (CPAA) and peptide in the form of a diagnostic compound and/or pharmaceutical composition useful for a diagnostic method and/or therapeutic method for diagnosing and/or treating pathological conditions related to colorectal cancer and pancreatic cancer.SOLUTION: According to the present invention, a recombinant monoclonal antibody used as a diagnostic tool for the early detection of cancers or an immunohistochemical tool for distinguishing between slow pancreatic cancer and aggressive pancreatic cancer using a monoclonal antibody or part (peptide) of the monoclonal antibody, which has specificity to an antigen and epitope of CPAA.SELECTED DRAWING: None
机译:要解决的问题:提供诊断化合物和/或药物组合物形式的人结肠直肠和胰腺癌相关抗原(CPAA)和肽,用于诊断和/或治疗病理学的诊断方法和/或治疗方法结直肠癌和胰腺癌的相关疾病。解决方案:根据本发明,使用单克隆抗体的重组单克隆抗体可用作癌症早期诊断的诊断工具或用于区分慢胰腺癌和侵袭性胰腺癌的免疫组化工具对CPAA的抗原和表位具有特异性的单克隆抗体的一部分或一部分(肽)。

著录项

  • 公开/公告号JP2017123851A

    专利类型

  • 公开/公告日2017-07-20

    原文格式PDF

  • 申请/专利权人 NEOGENIX ONCOLOGY INC;

    申请/专利号JP20170022169

  • 发明设计人 J ANDREW BRISTOL;JUDITH A KANTOR;

    申请日2017-02-09

  • 分类号C12N15/09;C07K16/30;C12Q1/04;C12N15/02;G01N33/574;A61K39/395;A61K45;A61P43;A61P35;A61P1;A61P1/18;C12P21/08;

  • 国家 JP

  • 入库时间 2022-08-21 14:01:29

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