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POLYPEPTIDE ISOLATED FROM BREVIBACTERIUM AURANTIACUM AND USE THEREOF FOR TREATMENT OF CANCER

机译:从金黄色芽孢杆菌分离的多肽及其在癌症治疗中的用途

摘要

PROBLEM TO BE SOLVED: To provide a method and pharmaceutical composition intended for the treatment of cancer.SOLUTION: According to the present invention, a polypeptide is isolated from Brevibacterium aurantiacum and exhibits methionine gamma-lyase activity and homocysteinase activity. A method for producing a polypeptide comprises isolating nucleic acid encoding the polypeptide and using a transformed host cell. A method uses the polypeptide for treatment of cancer.SELECTED DRAWING: None
机译:解决的问题:提供用于治疗癌症的方法和药物组合物。解决方案:根据本发明,从奥氏短杆菌属中分离出多肽,该多肽具有蛋氨酸γ-裂合酶活性和高半胱氨酸酶活性。产生多肽的方法包括分离编码该多肽的核酸并使用转化的宿主细胞。一种使用该多肽治疗癌症的方法。

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